Despite recent advances, women trail men in political participation, especially in developing countries where the long-term economic benefits from empowering women politically have not been well-researched. We use data from 163 villages of 12 main Indian states to explore whether requiring that village leadership positions be held by women (political reservation) affected uptake of economic opportunities via the National Rural Employment Guarantee Scheme. Reservation triggered increases in women's demand for work, program participation, and access to financial services that were sustained beyond the period of female political leadership. Enhanced female participation in program oversight, civic engagement, and electoral participation are plausible channels for such effects and political and economic empowerment seem to be complementary.